Free Shipping on orders over $25

Book Details

  • Paperback
  • Bookstore's Wholesale Price: $49.56
  • February 2016
  • ISBN: 978-0-815-34512-1
  • Territory Rights: Worldwide

More Textbooks

  1. Biology
    1. Immunology

Case Studies in Immunology

A Clinical Companion

Seventh Edition


See all options and formats starting at

Raif S. Geha (Author), Luigi Notarangelo (Author)


The perfect clinical companion for your immunology course

Case Studies in Immunology presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms of that specific disorder. The cases themselves demonstrate how immunological problems are deconstructed in the clinic and each one is followed by a concise summary of the clinical finding with questions that serve as discussion points.


For access to student resources, please contact W. W. Norton customer support at

The perfect companion for Janeway’s Immunology and The Immune System

With a total of 55 cases, this text can be used standalone, as a review aid, or as a companion to Janeway’s Immunobiology and The Immune System. Case Studies in Immunology adds a clinical dimension to the teaching of an inherently medically oriented discipline. 

A consistent learning structure promotes understanding

Each case is presented in the same format to illustrate, in a clinical context, essential points about the mechanism of immunity. Additionally, the cases explain some of the immunological problems often seen in the clinic and, when possible, show how human immune disorders may lead to targeted interventions. 

Updated and expanded coverage

This collection has been thoroughly updated and expanded to keep pace with the rapidly advancing field of immunology. The addition of new cases ensures that all students, especially those in or preparing for medical careers, learn and understand the impact that disorders of the immune system have on human health. 

    1. X-linked Agammaglobulinemia
    2. CD40 Ligand Deficiency
    3. Activation-Induced Cytidine Deaminase Deficiency
    4. Common Variable Immunodeficiency
    5. X-linked Severe Combined Immunodeficiency
    6. Adenosine Deaminase Deficiency
    7. Omenn Syndrome
    8. MHC Class II Deficiency
    9. DiGeorge Syndrome
    10. Acquired Immune Deficiency Syndrome (AIDS)
    11. Graft-Versus-Host Disease
    12. MHC Class I Deficiency
    13. X-linked Lymphoproliferative Syndrome
    14. Hemophagocytic Lymphohistiocytosis
    15. Chediak–Higashi Syndrome
    16. Wiskott-Aldrich Syndrome
    17. Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED)
    18. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease
    19. Autoimmune Lymphoproliferative Syndrome (ALPS)
    20. Hyper IgE Syndrome
    21. Ataxia Telangiectasia
    22. Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome (WHIM Syndrome)
    23. X-linked Hypohidrotic Ectodermal Dysplasia and Immunodeficiency
    24. Interferon-γ Receptor Deficiency
    25. Severe Congenital Neutropenia
    26. Chronic Granulomatous Disease
    27. Leukocyte Adhesion Deficiency
    28. Recurrent Herpes Simplex Encephalitis
    29. Interleukin 1 Receptor-Associated Kinase 4 Deficiency
    30. Congenital Asplenia
    31. Hereditary Angioedema
    32. Deficiency of the C8 Complement Component
    33. Hereditary Periodic Fever Syndromes
    34. Systemic Juvenile Idiopathic Arthritis
    35. Rheumatoid Arthritis
    36. Systemic Lupus Erythematosus
    37. Crohn’s Disease
    38. Multiple Sclerosis
    39. Autoimmune Hemolytic Anemia
    40. Myasthenia Gravis
    41. Pemphigus Vulgaris
    42. Celiac Disease
    43. Acute Infectious Mononucleosis
    44. Hemolytic Disease of the Newborn
    45. Toxic Shock Syndrome
    46. Lepromatous Leprosy
    47. Allergic Asthma
    48. Drug-induced Serum Sickness
    49. Contact Sensitivity to Poison Ivy
    50. Dedicator of Cytokinesis 8 Deficiency
    51. Activated PI3KD Syndrome (APDS)
    52. Increased Susceptibility to Candida Infections
    53. LPS-Responsive Beige-Like Anchor (LRBA) Deficiency
    54. T Cell Signaling Defects
    55. Channelopathies