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Book Details

  • Paperback + Digital Product License Key Folder
  • Bookstore's Wholesale Price: $154.70
  • July 2017
  • ISBN: 978-0-393-61508-1
  • 1344 pages
  • Territory Rights: Worldwide
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Roger L. Miesfeld (Author, University of Arizona), Megan M. McEvoy (Author, University of California, Los Angeles)


Biochemistry promotes understanding of biochemical concepts through highly readable chapters that consistently integrate stunning graphics with text. Its distinctive table of contents highlights how biochemical processes work, and applications to everyday biochemistry ensure that students develop a complete understanding of why biochemistry matters.


Visuals are the foundation

Miesfeld and McEvoy built each chapter around essential figures to strengthen students' understanding of how biochemistry processes and structures work. In-figure captions, numbered steps, and icons help students navigate the most complex biochemical processes. The vibrant, precise, and information-rich molecular representations in the text are paired with state-of-the-art 3D interactive versions in the online homework, and cutting-edge animations—many created using 3D technology—reinforce the book's visual emphasis. Watch a video on the visual approach.

Exceptionally clear with a distinctive chapter sequence

The text's distinctive chapter sequence highlights connections between key biochemical processes, encouraging students to consider how biochemistry works. Watch a video on the Chemistry/Biology balance. The table of contents emphasizes three big ideas: (1) the interdependence of energy conversion processes, (2) the role of signal transduction in metabolic regulation, and (3) biochemical processes affecting human health and disease, which ensure students develop a complete understanding of why biochemistry matters. The pedagogical foundation for each of these themes is that molecular structure determines chemical function. Watch a video explaining the book's structure.

Emphasis on applications and biomedical examples

Miesfeld and McEvoy consistently show why biochemistry matters. Opening vignettes provide an in-depth introduction to a biomedical application connected to the chapter's central topic. Real-life examples from nature help students understand how structure (of a protein, lipid, carbohydrate, and more) impacts function. Additionally, human health examples, particularly discussions of human disease, mentioned throughout the text are especially relevant for the many students who pursue careers in medicine. Watch a video describing the applied biochemistry.

Thoughtful pedagogy and assessment

Biochemistry promotes mastery of biochemical concepts through its effective pedagogy. Concept Integration questions at the end of many numbered chapter sections challenge students to think critically and synthesize the concepts. Additional end-of-chapter pedagogy includes a plentiful, balanced mix of basic Chapter Review questions and thought-provoking Challenge Problems. Smartwork5 online homework offers book-specific assessment through an array of exercises including art-based interactive questions, interactive 3D molecular visualization questions, and much more. Watch a video of Miesfeld describing his teaching challenges.

     PART 1 Principles of Biochemistry
    1 Principles of Biochemistry
    2 Physical Biochemistry: Energy Conversion, Water, and Membranes
    3 Nucleic Acid Structure and Function

    PART 2. Protein Biochemistry
    4 Protein Structure
    5 Methods in Protein Biochemistry
    6 Protein Function
    7 Enzyme Mechanisms
    8 Cell Signaling Systems

    PART 3. Energy Conversion Pathways
    9 Glycolysis: A Paradigm of Metabolic Regulation
    10.The Citrate Cycle
    11 Oxidative Phosphorylation
    12 Photosynthesis

    PART 4. Metabolic Regulation
    13 Carbohydrate Structure and Function
    14 Carbohydrate Metabolism
    15 Lipid Structure and Function
    16 Lipid Metabolism
    17 Amino Acid Metabolism
    18 Nucleotide Metabolism
    19 Metabolic Integration

    PART 5. Genomic Regulation
    20 DNA Replication, Repair, and Recombination
    21 RNA Synthesis, processing, and Gene Silencing
    22 Protein Synthesis, Posttranslational Modification, and Transport
    23 Gene Regulation